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DIR-B8-H8D-AFD4/LVL 2·Guided ArbitrageGuided multi-step solo arbitrage producing a concrete deliverable. Requires basic commercial judgment. Examples: formatting extracted data into a $99 compliance checklist and cold-emailing 500 affected businesses; translating a buried scientific abstract into a viral short-form script monetised via affiliate links./85% confidence
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Build NIH Ophthalmology Startup Directory via Public Grant Scraping

Organization
NIH RePORTER database (unstructured ophthalmology grant data)
Sector
Ophthalmology-focused investors, pharma scouts, and industry analysts
Location
Location unspecified
// Venture Capital// Biotech// Broadcasting & Publishing// Data Scraping// Talent Scouting// Frontend// Health Policy & Regulation// Data Engineering & Pipelines

Executive summary

Current state

NIH awarded $311,049 Phase I STTR funding to OUTFLOWGEN LLC for a first-in-class CRISPR glaucoma therapy, creating a predictable commercial gap where scientific validation exists but commercialization infrastructure is absent. The structural asymmetry is between NIH's ability to fund early science and small biotechs' inability to navigate the regulatory and capital requirements for clinical development.

Market catalyst

NIH's ophthalmology funding is scattered across hundreds of grants with no centralized directory. Investors and pharma scouts waste hours manually searching RePORTER instead of having a curated, filterable list of commercial opportunities.

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